Dennis R. Holmes, M.D. is the Associate Professor of Surgery at the John Wayne Cancer Institute in Santa Monica, California. As a dedicated breast surgeon, Dr. Holmes has dedicated his career to breast cancer treatment innovation through clinical research. He was an early investigator in the TARGIT-A clinical trial that evaluated the effectiveness of targeted intraoperative radiotherapy as an alternative to conventional whole breast radiotherapy. He currently serves as Co-Principal Investigator of the TARGIT U.S. Registry Trial and as President of the TARGIT Collaborative Group, a national organization of surgeons, radiation oncologists, and physicists committed to improving cancer patient care through education, patient advocacy, mentorship, and collaborative research. Dr. Holmes also serves as national principal investigator of the FROST (Cryoablation) Trial. Dr. Holmes currently holds the position of Program Chair of the upcoming 2019 American Society of Breast Surgeons 20th Annual Meeting; co-chair of the Oncoplastic Surgery Committee; chair of the Video Library Subcommittee; and chaired the development of the society’s performance and practice guideline for the use of neoadjuvant systemic therapy in the management of breast cancer.
