Prof. Stephen Johnston is Professor of Breast Cancer Medicine and Consultant Medical Oncologist at the Royal Marsden NHS Foundation Trust & Institute of Cancer Research, London. He was the first Director of the UK’s National Institute for Health Research (NIHR) Biomedical Research Centre for Cancer at the Royal Marsden. He graduated in 1983 from Trinity College at The University of Cambridge, and in 1986 from The Medical School at The University of Newcastle upon Tyne. He trained in General Medicine at St Bartholomew’s Hospital and Hammersmith Hospital in London, and subsequently in Medical Oncology at the Royal Marsden Hospital. He gained his PhD from the Institute of Cancer Research at the University of London, and took up his current position as Medical Oncologist on the Breast Unit at the Royal Marsden Hospital in 1997. He has a specialist interest in the treatment of metastatic breast cancer, and his major research interests lie in understanding mechanisms of endocrine resistance in breast cancer. He is actively involved in facilitating the interface between basic and applied research, and is chief investigator of several phase II / III trials of novel therapeutic approaches in advanced disease, including new endocrine therapies and targeted signal transduction inhibitors. He has published over 230 breast cancer related articles in peer-reviewed journals, and is a regular invited lecturer at national & international meetings. He is a member of several scientific committees and advisory boards, a Faculty Member at the American Society for Clinical Oncology, the Deputy-Editor of the international journal ‘Breast Cancer Research’, and a former Trustee of the UK charity ‘Breast Cancer Campaign’ having also been Chairman of their Scientific Advisory Board.